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CYSS Researchers

Discover the amazing findings of our CYSS researchers in the field of Synthetic Biology and learn about the fascinating innovations that are changing the way we think about science and technology.
Enhancing Bacterial Cellulose Production

Enhancing Bacterial Cellulose Production

Davide Bersanetti

Davide Bersanetti is studying ways to improve bacterial cellulose production by enhancing the genomic stability of Komagataeibacter bacteria. Unlike plant-derived cellulose, bacterial cellulose is highly pure and has useful properties for medical applications, such as artificial skin for burn treatment. However, its large-scale production is limited by the bacteria’s genomic instability. To address this, Bersanetti is using transposons ("jumping genes") to remove non-essential genetic material, aiming to create more stable and efficient bacterial strains. His research contributes to improving bacterial cellulose production, complementing existing efforts focused on fermentation and growth conditions.

Synthetic Biology Video Game

Synthetic Biology Video Game

Aarni Aspi

Aarni Aspi is developing a groundbreaking educational video game that immerses players in the world of synthetic biology. Originally designed as a teaching tool to complement university courses, the game has evolved into a platform for science popularization and citizen science. By integrating real-world BioBricks databases, players can design genetic constructs without needing prior expertise. Through an engaging storyline—where players take on the role of an intern solving the mysterious disappearance of a professor—the game combines storytelling, ethics, and real-world applications to make synthetic biology more accessible and inspiring.

Biomaterials from Microbial Chitin

Biomaterials from Microbial Chitin

An Ngyen

Doctoral student An Nguyen employs synthetic biology to develop cost-effective, sustainable biomaterials. Originating from plastic-burdened Vietnam, An's research centers on producing chitin and chitosan from microbial sources. By stressing fungal organisms, An enhances chitin output, tapping into the entire biomass for value.

Microbial Self-healing Materials

Microbial Self-healing Materials

Manuel Arias Barrantes

Researcher Manuel Arias Barrantes pioneers a multidisciplinary approach blending science and design, to unlock the potential of microbial self-healing. Barrantes is working with living materials that could autonomously regenerate, defying the wear and tear of everyday use.

Accelerating drug discovery with AI

Accelerating drug discovery with AI

Mary Astero

Doctoral researcher Mary Astero, is harnessing the power of artificial intelligence (AI) and deep learning to expedite the complex process of synthesizing new drugs through streamlining retrosynthesis.

New pathways for microbial pigments

New pathways for microbial pigments

Pradhuman Jetha

Research scientist Pradhuman Jethas work focuses on unveiling novel biosynthetic pathways for bio-based pigments. By deciphering the genomic secrets behind the captivating red color pigment of Cortinarius semisanguineus mushrooms, Jetha envisions harnessing these pathways within microbial hosts, cultivating year-round color production in compact bioreactors.

Predicting the future catalytic activity of enzymes

Predicting the future catalytic activity of enzymes

Robert Armah-Sekum

Doctoral student Robert Armah-Sekums research aims to forecast the catalytic activity and substrate interaction of enzymes, circumventing arduous trial-and-error experimentation. By using AI and computational modeling, Armah-Sekum is able to predict the functions of proteins by unraveling the intricate interplay between protein attributes, structure, and function.

AI assited enzyme design for improved bioplastics

AI assited enzyme design for improved bioplastics

Tuula Tenkanen

Research Scientist Tuula Tenkanen combines AI, synthetic biology and enzyme design to revolutionize bioplastics. She develops new to nature polyhydroxyalkanoates (PHAs), biobased polymers with versatile properties, and employs AI to design enzymes for efficient biosynthesis.

Mechanism of assembly of biological materials inside cells

Mechanism of assembly of biological materials inside cells

Feng Jianhui

One of the future impacts of synthetic biology will be biosynthetic production in microbes of materials such as silk or composites that can both outperform and replace alternatives made from oil today.

Reinforcement learning for microbial strain design

Reinforcement learning for microbial strain design

Maryam Sabzevari

Post-docoral researcher Maryam Sabzevari’s research deals with using artificial intelligence (AI) to design cell factories. Synthetic biology enables building of novel efficient production strains for desired products.

Expansin-like proteins for bio-based materials engineering

Expansin-like proteins for bio-based materials engineering

Taru Koitto

Lignocellulose and chitin, the most abundant polysaccharide resources in the world, could be used to replace oil in production. Taru’s approach is to upgrade the intrinsic structure of these polysaccharides.

New Bioplastics with Microbes

New Bioplastics with Microbes

Anna Ylinen

Research scientist Anna Ylinen is doing her doctoral thesis at the Center for Young Synbio Scientists on microbial bioplastics.

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